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Syntaxin 1A / STX1A (1-226) Human Protein

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SKU
AR09086PU-N
Recombinant human Syntaxin 1A protein
Size:
100 ug
  $455.00
3 Weeks*
Bulk/Customize

Other products for "STX1A or NM_001165903"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MKDRTQELRT AKDSDDDDDV AVTVDRDRFM DEFFEQVEEI RGFIDKIAEN VEEVKRKHSA ILASPNPDEK TKEELEELMS DIKKTANKVR SKLKSIEQSI EQEEGLNRSS ADLRIRKTQH STLSRKFVEV MSEYNATQSD YRERCKGRIQ RQLEITGRTT TSEELEDMLE SGNPAIFASG IIMDSSISKQ ALSEIETRHS EIIKLENSIR ELHDMFMDMA MLVESQ
Predicted MW 26.1 kDa (226aa) confirmed by MALDI-TOF
Concentration 1mg/ml (determined by Bradford assay)
Purity > 95% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 10% glycerol
Preparation Liquid purified protein
Recommended Dilution SDS-PAGE
Protein Description Recombinant syntaxin 1A protein (1-226aa) contains N-terminal domain (Habc) and t_SNARE domain (H3 domain) and this protein was overexpressed in E.coli and purified by using the conventional column chromatography techniques.
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_004594.1
Locus ID 6804
UniProt ID Q16623
Cytogenetics 7q11.23
Synonyms STX1A, STX1, Syntaxin 1A, Neuron-specific antigen HPC-1, Syntaxin-1A, HPC 1, Neuron specific antigen HPC1, STX1, Syntaxin 1A brain.
Summary This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, Sep 2009
Protein Categories Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways SNARE interactions in vesicular transport
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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