RAC1 (1-192) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Predicted MW | 21.4 kDa (192aa) confirmed by MALDI-TOF |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 2mM EDTA, 1mM DTT, 10% Glycerol |
| Preparation | Liquid purified protein |
| Recommended Dilution | SDS-PAGE |
| Protein Description | Recombinant human RAC1 was expressed in E.coli and purified by using conventional chromatography techniques. |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_008839.2 |
| Locus ID | 5879 |
| UniProt ID | P63000 |
| Cytogenetics | 7p22.1 |
| Synonyms | Ras-related C3 botulinum toxin substrate 1 isoform Rac1, RAC1, RAC1, p21-Rac1, Ras-like protein TC25, Cell migration-inducing gene 5 protein, Ras-related C3 botulinum toxin substrate 1, Ras-related C3 botulinum toxin substrate 1 isoform Rac1 MGC111543, MIG 5, MIG5, Migration inducing gene 5, Migration inducing protein 5, p21 Rac1, Rac 1, Ras like protein TC25, Ras related C3 botulinum toxin substrate 1, Rho family small GTP binding protein Rac1, TC 25 |
| Summary | The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Mar 2009 |
| Protein Categories | Growth Factors, Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Adherens junction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, Chemokine signaling pathway, Colorectal cancer, Epithelial cell signaling in Helicobacter pylori infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Pancreatic cancer, Pathways in cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, Toll-like receptor signaling pathway, VEGF signaling pathway, Viral myocarditis, Wnt signaling pathway |
Reviews
Documents
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Resources
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Citations
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