Protein phosphatase 1G / PPM1G (317-546, His-Tag) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | His-Tag |
| Predicted MW | 27 kDa (250aa) confirmed by MALDI-TOF |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 25mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 1mM EDTA, 2mM beta-mercaptoethanol, 20% glycerol |
| Preparation | Liquid purified protein |
| Recommended Dilution | SDS-PAGE |
| Protein Description | Recombinant human PPM1G, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography techniques. |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_002698 |
| Locus ID | 5496 |
| UniProt ID | O15355 |
| Cytogenetics | 2p23.3 |
| Synonyms | PP2CG; PP2CGAMMA; PPP2CG |
| Summary | The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. provided by RefSeq, Apr 2010 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome, Phosphatase |
Reviews
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Resources
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Citations
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