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KiSS-1 (1-120) Human Protein

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SKU
AR09057PU-L
Recombinant human KISS1 protein
Size:
500 ug
  $1,135.00
3 Weeks*
Bulk/Customize

Other products for "KISS1 or NM_002256"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MEPLEKVASV GNSRPTGQQL ESLGLLAPGE QSLPCTERKP AATARLSRRG TSLSPPPESS GSPQQPGLSA PHSRQIPAPQ GAVLVQREKD LPNYNWNSFG LRFGKREAAP GNHGRSAGRG
Predicted MW 12.6 kDa (120aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Concentration 1mg/ml (determined by absorbance at 280nm)
Purity > 90% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Preparation Liquid purified protein
Recommended Dilution SDS-PAGE
Protein Description Recombinant KISS1 protein was expressed in E.coli and purified by using conventional chromatography techniques.
Note (Real molecular weight on SDS-PAGE will be shift up)
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_002247
Locus ID 3814
UniProt ID Q15726
Cytogenetics 1q32.1
Synonyms KiSS-1 metastasis suppressor, Prepro-kisspeptin, Kisspeptin, Metastin
Summary This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. provided by RefSeq, Mar 2012
Protein Categories Endocrine and metabolic diseases, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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