Ferritin light chain (FTL) (1-175) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Predicted MW | 20kDa (175aa) |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 20mM Tris-HCl buffer (pH 7.5) |
| Preparation | Liquid purified protein |
| Recommended Dilution | SDS-PAGE |
| Protein Description | Recombinant human FTL was expressed in E.coli and purified by conventional chromatography techniques. |
| Note | NCBI Accession No.: NP_000137 |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_000137.2 |
| Locus ID | 2512 |
| UniProt ID | P02792 |
| Cytogenetics | 19q13.33 |
| Synonyms | Ferritin light polypeptide 1, Ferritin L subunit, Ferritin, light polypeptide 1, FTL, Ferritin, light polypeptide 1 Ferritin H subunit, Ferritin heavy chain like, Ferritin heavy polypeptide 1, Ferritin light chain like, Ferritin light polypeptide, Ferritin, heavy polypeptide, FTH, FTH1, FTL protein. |
| Summary | This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins, Nervous system: Neurodegenerative diseases |
| Protein Families | Druggable Genome |
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