PMP2 (1-132) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Predicted MW | 14.9 kDa (132aa) confirmed by MALDI-TOF |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 2mM EDTA, 1mM DTT, 10% glycerol |
| Preparation | Liquid purified protein |
| Recommended Dilution | SDS-PAGE |
| Protein Description | Recombinant PMP2 protein was expressed in E.coli and purified by using conventional chromatography techniques. |
| Note | NCBI Accession No.: NP_002668 |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_002668 |
| Locus ID | 5375 |
| UniProt ID | P02689 |
| Cytogenetics | 8q21.13 |
| Synonyms | Peripheral myelin protein 2, P2, MP2, FABP8, M-FABP, Myelin P2 protein, Peripheral myelin protein 2, PMP2, Peripheral myelin protein 2 |
| Summary | The protein encoded by this gene localizes to myelin sheaths of the peripheral nervous system. The encoded protein can bind both the membrane layers of the sheaths and monomeric lipids, and is thought to provide stability to the sheath. A defect in this gene was shown to be a cause of dominant demyelinating CMT neuropathy. provided by RefSeq, Jan 2017 |
| Protein Categories | Intracellular Proteins, Nervous system: Neurodegenerative diseases |
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