Adiponectin (18-247) Mouse Protein

CAT#: AR09000PU-S

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Adiponectin (18-247) mouse recombinant protein, 0.1 mg



USD 330.00


Availability*
3 Weeks

Size
    • 100 ug


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Specifications

Product Data
Description Adiponectin (18-247) mouse recombinant protein, 0.1 mg
Species Mouse
Expression Host E. coli
Expression cDNA Clone or AA Sequence MGSSHHHHHH SSGLVPRGSH MEDDVTTTEE LAPALVPPPK GTCAGWMAGI PGHPGHNGTP GRDGRDGTPG EKGEKGDAGL LGPKGETGDV GMTGAEGPRG FPGTPGRKGE PGEAAYVYRS AFSVGLETRV TVPNVPIRFT KIFYNQQNHY DGSTGKFYCN IPGLYYFSYH ITVYMKDVKV SLFKKDKAVL FTYDQYQEKN VDQASGSVLL HLEVGDQVWL QVYGDGDHNG LYADNVNDST FTGFLLYHDT N
Predicted MW 27 kDa
Concentration lot specific
Purity >90% > / = 90% by SDS-PAGE
Buffer Presentation State: Purified
State: Liquid
Buffer System: 20 mM Tris pH 8.0, 1 mM DTT, 10% Glycerol
Preparation Liquid
Protein Description Recombinant mouse adiponectin, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage Store at -20°C. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_033735
Locus ID 11450
UniProt ID Q60994
Cytogenetics 16 13.96 cM
Synonyms 30kDa; Acdc; Acrp30; Ad; Adid; adipo; apM1; APN; GBP28
Summary Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.[UniProtKB/Swiss-Prot Function]
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