Interleukin-6 / IL6 Chicken Protein

CAT#: AR05234PU-S

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Interleukin-6 / IL6 chicken recombinant protein, 50 µg

USD 485.00

5 Days

    • 50 ug

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Product Data
Description Interleukin-6 / IL6 chicken recombinant protein, 50 µg
Species Chicken
Concentration lot specific
Purity >85% by Ni Chelate chromatography
Buffer State: Liquid purified protein
Buffer System: Phosphate buffered saline
Preparation Liquid purified protein
Applications Functional Assays.
In vitro Assay.
Protein Description His-tagged recombinant interleukin-6 expressed in E.coli. Thsi protein induces corticosterone secretion in vivo and induces proliferation of the IL-6 dependant murine hybridoma cell line 7TD1 in vitro.
Storage Store the protein at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: 3 month from despatch.
Reference Data
RefSeq NP_000591
Locus ID 3569
Cytogenetics 7p15.3
Synonyms BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6
Summary This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). [provided by RefSeq, Aug 2020]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Graft-versus-host disease, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Jak-STAT signaling pathway, NOD-like receptor signaling pathway, Pathways in cancer, Prion diseases, Toll-like receptor signaling pathway


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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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