Neuropeptide Y / NPY Human Protein

SKU AR05070PU-N

Neuropeptide Y / NPY human protein, 0.1 mg

Product Data

• Species: Human
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Y-P-S-K-P-D-N-P-G-E-D-A-P-A-E-D-M-A-R-Y-Y-S-A-L-R-H-Y-I-N-L-I-T-R-Q-R-Y-NH2
• Concentration: lot specific
• Purity: >97% pure by HPLC
• Presentation State: Purified
• Buffer: Presentation State: Purified; State: Liquid purified synthetic peptide; Preservative: None; Stabilizer: None
• Preparation: Liquid purified synthetic peptide
• Recommended Dilution: ELISA.
• Protein Description: Synthetic Human Neuropeptide Tyrosine prepared by solid phase synthesis.
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice

Reference Data

• RefSeq: NP_000896
• Locus ID: 4852
• UniProt ID: P01303
• Cytogenetics: 7p15.3
• Synonyms: PYY4
• Summary: This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]
• Protein Families: <strong>ELISA.</strong>
• Protein Pathways: Adipocytokine signaling pathway