SNAP25B (1-206) Human Protein

SKU
AR03038PU-N
Recombinant human SNAP25 protein
  $455.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MAEDADMRNE LEEMQRRADQ LADESLESTR RMLQLVEESK DAGIRTLVML DEQGEQLERI EEGMDQINKD MKEAEKNLTD LGKFCGLCVC PCNKLKSSDA YKKAWGNNQD GVVASQPARV VDEREQMAIS GGFIRRVTND ARENEMDENL EQVSGIIGNL RHMALDMGNE IDTQNRQIDR IMEKADSNKT RIDEANQRAT KMLGSG
Tag His-tag
Predicted MW 23.3 kDa (206aa) confirmed by MALDI-TOF
Concentration 1mg/ml (determined by Bradford assay)
Purity > 90% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 25mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 10% glycerol
Preparation Liquid purified protein
Recommended Dilution SDS-PAGE
Protein Description
Recombinant human SNAP25, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_570824.1
Locus ID 6616
UniProt ID P60880
Cytogenetics 20p12.2
Synonyms Synaptosomal-associated protein 25 isoform SNAP25B, FLJ23079, SNAP25, RIC-4, RIC4, SEC9, SNAP, SNAP-25, Synaptosomal-associated protein 25 isoform SNAP25B, Synaptosomal-associated protein 25 isoform SNAP25B SuP, Super protein, bA416N4.2, Bdr, dJ1068F16.2, HGNC:11132, MGC105414, MGC139754, Resistance to inhibitors of cholinesterase 4 homolog, RIC 4, SEC9, SNAP 25, SNAP-25B, SNP 25, SNP25, sp, Synaptosomal associated 25 kDa protein, Synaptosomal associated protein, Synaptosomal associated protein 25, Synaptosomal associated protein 25kDa.
Summary Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. provided by RefSeq, Jul 2008
Protein Categories Growth Factors, Intracellular Proteins, Nervous system Diseases
Protein Families Druggable Genome
Protein Pathways SNARE interactions in vesicular transport
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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