Herbimycin A Protein

SKU
AR03028PU-S
Herbimycin A protein, 0.1 mg
  $430.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Predicted MW 574.3
Purity >98% 98%
Presentation State Purified
Buffer Presentation State: Purified
State: Lyophilized solid; yellow
Reconstitution Method Soluble in DMSO and ethanol (1 mg/ml)
Preparation Lyophilized solid; yellow
Recommended Dilution Protocol: 1. Uehara Y.,and Fukazawa H. (1991) Methods Enzymol. 201: 370.
2. Fukazawa H., et al. (1991) Biochem. Pharmacol. 42: 1661.
3. Satoh T., et al.(1992) J.Biol.Chem. 267: 2537.
4. Weiss R., and Nuccitelli R. (1992) J.Biol.Chem. 267:5608.
Protein Description Formula: C30H42N2O9
Storage Store the antibody (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
Avoid repeated freezing and thawing.
Protect from light!
Stability Shelf life: One year from despatch.
Shipping Blue Ice
Reference Data
Summary Herbimycin A, a benzoquinoid ansamycin antibiotic, irreversibly and selectively inhibits tyrosine kinases by reacting with thiol groups (1,2). It is effective on Src, Yes, Fps, Ros, Abl and ErbB oncogene products (1-3) and inhibits thrombin-induced tyrosine phosphorylation of phospholipase C (4).
Protein Families and Fukazawa H. (1991) Methods Enzymol. 201: 370.
2. Fukazawa H., and Nuccitelli R. (1992) J.Biol.Chem. 267:5608., et al. (1991) Biochem. Pharmacol. 42: 1661.
3. Satoh T., et al.(1992) J.Biol.Chem. 267: 2537.
4. Weiss R., Protocol: 1. Uehara Y.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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