HSPA8 / HSC70 (active) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Concentration | lot specific |
| Purity | >90% pure as determined by SDS-PAGE analysis. |
| Presentation State | Aff - Purified |
| Buffer | Presentation State: Aff - Purified State: Liquid affinity purified protein Buffer System: Na-Phosphate, pH 7.5 (20 mM), 150 mM NaCl, 10% Glycerol, 200 mM Imidazole. |
| Preparation | Liquid affinity purified protein |
| Recommended Dilution | ATPase Assay, WB control, Binding Assays, ELISA reference standard. This protein has ATPase activity at the time of manufacture of 3.2 uM phosphate liberated/hr/ug protein in a 200 uL reaction at 37 C (pH 7.5) in the presence of 20 uL of 1 mM ATP using a Malachite Green assay. |
| Protein Description | Recombinant Human Hsc70 Protein with ATPase activity, his-tagged |
| Storage | Store the antibody (in aliquots) at -20°C. Can be shipped at 2-8 °C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: One year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_006588 |
| Locus ID | 3312 |
| UniProt ID | P11142 |
| Cytogenetics | 11q24.1 |
| Synonyms | HSP73, HSPA10, Heat shock cognate 71 kDa protein, Heat shock 70 kDa protein 8 |
| Summary | This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Aug 2011 |
| Protein Categories | Intracellular Proteins |
| Protein Families | ATPase Assay, Binding Assays, ELISA reference standard. This protein has ATPase activity at the time of manufacture of 3.2 uM phosphate liberated/hr/ug protein in a 200 uL reaction at 37 C (pH 7.5) in the presence of 20 uL of 1 mM ATP using a Malachite Green assay., WB control |
| Protein Pathways | Antigen processing and presentation, Endocytosis, MAPK signaling pathway, Spliceosome |
Reviews
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Resources
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Citations
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