HSPA8 / HSC70 (active) Human Protein

SKU AR03020PU-N

HSPA8 / HSC70 (active) human recombinant protein, 0.1 mg

Product Data

• Species: Human
• Expression Host: E. coli
• Concentration: lot specific
• Purity: >90% pure as determined by SDS-PAGE analysis.
• Presentation State: Aff - Purified
• Buffer: Presentation State: Aff - Purified; State: Liquid affinity purified protein; Buffer System: Na-Phosphate, pH 7.5 (20 mM), 150 mM NaCl, 10% Glycerol, 200 mM Imidazole.
• Preparation: Liquid affinity purified protein
• Recommended Dilution: ATPase Assay, WB control, Binding Assays, ELISA reference standard.; This protein has ATPase activity at the time of manufacture of 3.2 uM phosphate liberated/hr/ug protein in a 200 uL reaction at 37 C (pH 7.5) in the presence of 20 uL of 1 mM ATP using a Malachite Green assay.
• Protein Description: Recombinant Human Hsc70 Protein with ATPase activity, his-tagged
• Storage: Store the antibody (in aliquots) at -20°C.; Can be shipped at 2-8 °C.; Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Shipping: Blue Ice

Reference Data

• RefSeq: NP_006588
• Locus ID: 3312
• UniProt ID: P11142
• Cytogenetics: 11q24.1
• Synonyms: HSP73, HSPA10, Heat shock cognate 71 kDa protein, Heat shock 70 kDa protein 8
• Summary: This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
• Protein Families: ATPase Assay, Binding Assays, ELISA reference standard.<br />This protein has ATPase activity at the time of manufacture of 3.2 uM phosphate liberated/hr/ug protein in a 200 uL reaction at 37 C (pH 7.5) in the presence of 20 uL of 1 mM ATP using a Malachite Green assay., WB control
• Protein Pathways: Antigen processing and presentation, Endocytosis, MAPK signaling pathway, Spliceosome