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IAP4 / BIRC5 (1-142, Calmodulin Tag) Human Protein

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SKU
AR03007PU-N
Recombinant human Survivin protein
Size:
100 ug
  $455.00
3 Weeks*
Bulk/Customize

Other products for "BIRC5 or NM_001012270"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MGAPTLPP AWQPFLKDHR ISTFKNWPFL EGCACTPERM AEAGFIHCPT ENEPDLAQCF FCFKELEGWE PDDDPIEEHK KHSSGCAFLS VKKQFEELTL GEFLKLDRER AKNKIAKETN NKKKEFEETA KKVRRAIEQL AAMD
Tag Calmodulin Tag
Predicted MW 33 kDa (294aa) confirmed by MALDI-TOF
Concentration 1mg/ml (determined by Bradford assay)
Purity > 90% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 0.1M NaCl
Endotoxin < 1 EU per 1ug of protein (determined by LAL method)
Preparation Liquid protein, purified by conventional chromatography techniques
Recommended Dilution SDS-PAGE
Protein Description Recombinant human Survivin fused to CaM-tag at N-terminus
Note NCBI Accession No: AAH34148
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: six months from despatch.
Shipping Blue Ice
Reference Data
RefSeq AAH34148.1
Locus ID 332
UniProt ID O15392
Cytogenetics 17q25.3
Synonyms Baculoviral IAP repeat-containing protein 5 isoform 1, BIRC5, Baculoviral IAP repeat-containing 5, API4, EPR-1, Baculoviral IAP repeat-containing protein 5 isoform 1, Survivin, Baculoviral IAP repeat-containing protein 5 isoform 1 API4, Apoptosis Inhibitor 4, Apoptosis inhibitor survivin, Apoptosis inhibitor4, Baculoviral IAP repeat containing 5, Baculoviral IAP repeat containing protein 5, BIRC 5, EPR 1, IAP4, SVV, TIAP.
Summary This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Jun 2011
Protein Categories Cytokines, Intracellular Proteins
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Colorectal cancer, Pathways in cancer
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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