IAP4 / BIRC5 (full length) Human Protein

SKU AR03007PU-N

IAP4 / BIRC5 (full length) human recombinant protein, 0.1 mg

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAKG SHMGAPTLPP AWQPFLKDHR ISTFKNWPFL EGCACTPERM AEAGFIHCPT ENEPDLAQCF FCFKELEGWE PDDDPIEEHK KHSSGCAFLS VKKQFEELTL GEFLKLDRER AKNKIAKETN NKKKEFEETA KKVRRAIEQL AAMD
• Predicted MW: 33 kDa
• Concentration: lot specific
• Purity: > 90% by SDS PAGE
• Presentation State: Purified
• Buffer: Presentation State: Purified; State: Liquid protein, purified by conventional chromatography techniques; Buffer System: 20 mM Tris pH 7.5, 0.1M NaCl
• Preparation: Liquid protein, purified by conventional chromatography techniques
• Protein Description: Recombinant human Survivin fused to CaM-tag at N-terminus
• Note: NCBI Accession No: AAH34148
• Storage: Store at -20 °C. Avoid repeated freezing and thawing.
• Stability: Shelf life: six months from despatch.
• Shipping: Blue Ice

Reference Data

• RefSeq: NP_001012270
• Locus ID: 332
• UniProt ID: O15392
• Cytogenetics: 17q25.3
• Synonyms: Survivin, Apoptosis inhibitor 4, API4
• Summary: This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Colorectal cancer, Pathways in cancer