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BIRC7 / LIVIN (1-298, His-Tag) Human Protein

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SKU
AR03006PU-L
Recombinant human Livin alpha protein
Size:
500 ug
  $1,480.00
3 Weeks*
Bulk/Customize

Other products for "BIRC7 or NM_022161"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MGPKDSAKCL HRGPQPSHWA AGDGPTQERC GPRSLGSPVL GLDTCRAWDH VDGQILGQLR PLTEEEEEEG AGATLSRGPA FPGMGSEELR LASFYDWPLT AEVPPELLAA AGFFHTGHQD KVRCFFCYGG LQSWKRGDDP WTEHAKWFPS CQFLLRSKGR DFVHSVQETH SQLLGSWDPW EEPEDAAPVA PSVPASGYPE LPTPRREVQS ESAQEPGGVS PAEAQRAWWV LEPPGARDVE AQLRRLQEER TCKVCLDRAV SIVFVPCGHL VCAECAPGLQ LCPICRAPVR SRVRTFLS
Tag His-Tag
Predicted MW 34.9 kDa (318aa) confirmed by MALDI-TOF
Concentration 1mg/ml (determined by Bradford assay)
Purity > 90% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 0.1M NaCl, 2mM EDTA, 20% glycerol
Preparation Liquid protein, purified by conventional chromatography techniques
Recommended Dilution SDS-PAGE
Protein Description Recombinant human Livin fused to His-tag at N-terminus
Note NCBI Accession No.: NP_647478
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: six months from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_647478
Locus ID 79444
UniProt ID Q96CA5
Cytogenetics 20q13.33
Synonyms Livin inhibitor of apoptosis isoform alpha, BIRC7, Baculoviral IAP repeat-containing 7, KIAP, MLIAP, RNF50, ML-IAP, KIAP, MLIAP, RNF50, Livin, Livin inhibitor of apoptosis isoform alpha, Livin inhibitor of apoptosis isoform alpha Baculoviral IAP repeat containing 7, Baculoviral IAP repeat containing protein 7, BIRC 7, Kidney inhibitor of apoptosis protein, Livin inhibitor of apotosis, RING finger protein 50, RNF 50, Melanoma inhibitor of apoptosis protein, ML IAP.
Summary This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants provided by RefSeq, Jul 2013
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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