DIABLO / SMAC (56-239) Human Protein

SKU AR03005PU-L

DIABLO / SMAC (56-239) human recombinant protein, 0.5 mg

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MASMTGGQQM GRGSMAVPIA QKSEPHSLSS EALMRRAVSL VTDSTSTFLS QTTYALIEAI TEYTKAVYTL TSLYRQYTSL LGKMNSEEED EVWQVIIGAR AEMTSKHQEY LKLETTWMTA VGLSEMAAEA AYQTGADQAS ITARNHIQLV KLQVEEVHQL SRKAETKLAE AQIEELRQKT QEEGEERAES EQEAYLRED
• Predicted MW: 22 kDa
• Concentration: lot specific
• Purity: >95% > 95 % by SDS PAGE
• Presentation State: Purified
• Buffer: Presentation State: Purified; State: Liquid protein, purified by conventional chromatography techniques; Buffer System: 20 mM Tris pH 7.5
• Preparation: Liquid protein, purified by conventional chromatography techniques
• Protein Description: Recombinant human Smac fused to T7-tag.
• Note: NCBI Accession No: NP_063940
• Storage: Store at -20°C. Avoid repeated freezing and thawing.
• Stability: Shelf life: six months from despatch.
• Shipping: Blue Ice

Reference Data

• RefSeq: NP_001265231
• Locus ID: 56616
• UniProt ID: Q9NR28
• Cytogenetics: 12q24.31
• Synonyms: DFNA64; SMAC
• Summary: This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
• Protein Families: Transmembrane