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DIABLO / SMAC (56-239, T7-Tag) Human Protein

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SKU
AR03005PU-L
Recombinant human SMAC/Diablo protein
Size:
500 ug
  $1,480.00
3 Weeks*
Bulk/Customize

Other products for "DIABLO or NM_001278302"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MASMTGGQQM GRGSMAVPIA QKSEPHSLSS EALMRRAVSL VTDSTSTFLS QTTYALIEAI TEYTKAVYTL TSLYRQYTSL LGKMNSEEED EVWQVIIGAR AEMTSKHQEY LKLETTWMTA VGLSEMAAEA AYQTGADQAS ITARNHIQLV KLQVEEVHQL SRKAETKLAE AQIEELRQKT QEEGEERAES EQEAYLRED
Tag T7-Tag
Predicted MW 22 kDa (199aa) confirmed by MALDI-TOF
Concentration 1mg/ml (determined by Bradford assay)
Purity > 95% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 20mM Tris-HCl buffer (pH 7.5)
Preparation Liquid protein, purified by conventional chromatography techniques
Recommended Dilution SDS-PAGE
Protein Description Recombinant human Smac fused to T7-tag.
Note NCBI Accession No: NP_063940
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: six months from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_063940
Locus ID 56616
UniProt ID Q9NR28
Cytogenetics 12q24.31
Synonyms Diablo isoform 1, SMAC3, DIABLO-S, FLJ10537, FLJ25049, Diablo isoform 1, SMAC/Diablo, Diablo isoform 1 0610041G12Rik, DBOH, Diablo homolog, DIABLO S, Diablo homolog (Drosophila), Mitochondrial Smac protein, Diablo homolog mitochondrial, SMAC 3, Smac protein, Direct IAP binding protein with low pI, Second mitochondria derived activator of caspase.
Summary This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, May 2013
Protein Categories Intracellular Proteins, Membrane Proteins, Nervous system Diseases
Protein Families Transmembrane
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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