MIF (1-115) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Predicted MW | 12 kDa (115aa) confirmed by MALDI-TOF |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Purity | > 98% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 50mM Tris-HCl buffer (pH 8.0) containing 0.5mM DTT 10% glycerol |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
| Preparation | Liquid, purified by conventional chromatograph techniques |
| Recommended Dilution | SDS-PAGE |
| Protein Description | Recombinant human MIF |
| Note | NCBI Accession No.: NP_002406 |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: six months from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_002406 |
| Locus ID | 4282 |
| UniProt ID | P14174 |
| Cytogenetics | 22q11.23 |
| Synonyms | Macrophage migration inhibitory factor, GLIF, MMIF, MIF, EC 5.3.2.1, Phenylpyruvate tautomerase, Glycosylation-inhibiting factor, GIF, Macrophage migration inhibitory factor, macrophage migration inhibitory factor (glycosylation-inhibiting factor) |
| Summary | This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. provided by RefSeq, Jul 2008 |
| Protein Categories | Allergies and autoimmune diseases, Chemokines, Cytokines, Intracellular Proteins, Secreated Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Phenylalanine metabolism, Tyrosine metabolism |
Reviews
Documents
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Resources
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Citations
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