NACA (NM_001113201) Human Mass Spec Standard

SKU
PH325258
NACA MS Standard C13 and N15-labeled recombinant protein (NP_001106672)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC225258
Predicted MW 23.2 kDa
Protein Sequence
Protein Sequence
>RC225258 representing NM_001113201
Red=Cloning site Green=Tags(s)

MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQS
RSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAA
EKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAI
MELTM

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001106672
RefSeq ORF 645
Synonyms HSD48; NAC-alpha; NACA1; skNAC
Locus ID 4666
UniProt ID Q13765
Cytogenetics 12q13.3
Summary This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes. provided by RefSeq, Feb 2016
Protein Families Druggable Genome, Transcription Factors
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Other "NACA" proteins (11)
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LY426388 Transient overexpression lysate of nascent polypeptide-associated complex alpha subunit (NACA), transcript variant 2 (as WB positive control) 100 ug
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LY426389 Transient overexpression lysate of nascent polypeptide-associated complex alpha subunit (NACA), transcript variant 4 (as WB positive control) 100 ug
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TP311268 Recombinant protein of human nascent polypeptide-associated complex alpha subunit (NACA), transcript variant 3, 20 µg 20 ug
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TP325257 Recombinant protein of human nascent polypeptide-associated complex alpha subunit (NACA), transcript variant 4, 20 µg 20 ug
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TP325258 Purified recombinant protein of Homo sapiens nascent polypeptide-associated complex alpha subunit (NACA), transcript variant 2, 20 µg 20 ug
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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