Small EDRK rich factor 1 (SERF1A) (NM_022968) Human Mass Spec Standard
CAT#: PH324986
SERF1A MS Standard C13 and N15-labeled recombinant protein (NP_075257)
Specifications
Product Data | |
Tag | C-Myc/DDK |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC224986 |
Predicted MW | 7.2 kDa |
Protein Sequence |
>RC224986 representing NM_022968
Red=Cloning site Green=Tags(s) MARGNQRELARQKNMKKTQEISKGKRKEDSLTASQRKQRDSEIMQEKQKAANEKKSMQTREK TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_075257 |
RefSeq ORF | 186 |
Synonyms | 4F5; FAM2A; H4F5; SERF1; SMAM1 |
Locus ID | 8293 |
UniProt ID | O75920 |
Cytogenetics | 5q13.2 |
Summary | This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The duplication region includes both a telomeric and a centromeric copy of this gene. Deletions of this gene, the telomeric copy, often accompany deletions of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients, and so it is thought that this gene may be a modifier of the SMA phenotype. The function of this protein is not known; however, it bears low-level homology with the RNA-binding domain of matrin-cyclophilin, a protein which colocalizes with small nuclear ribonucleoproteins (snRNPs) and the SMN1 gene product. Alternatively spliced transcripts have been documented but it is unclear whether alternative splicing occurs for both the centromeric and telomeric copies of the gene. [provided by RefSeq, Jul 2008] |
Protein Families | Transmembrane |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC411852 | SERF1A HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LC429713 | SERF1A HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LY411852 | Transient overexpression lysate of small EDRK-rich factor 1A (telomeric) (SERF1A), transcript variant 1 |
USD 436.00 |
|
LY429713 | Transient overexpression lysate of small EDRK-rich factor 1A (telomeric) (SERF1A), transcript variant 2 |
USD 436.00 |
|
TP324986 | Recombinant protein of human small EDRK-rich factor 1A (telomeric) (SERF1A), transcript variant 2, 20 µg |
USD 867.00 |
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