TORC1 (CRTC1) (NM_001098482) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC224693 |
| Predicted MW | 68.6 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001091952 |
| RefSeq Size | 7009 |
| RefSeq ORF | 1950 |
| Synonyms | Mam-2; MAML2; MECT1; TORC-1; TORC1; WAMTP1 |
| Locus ID | 23373 |
| UniProt ID | Q6UUV9 |
| Cytogenetics | 19p13.11 |
| Summary | Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity). In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.UniProtKB/Swiss-Prot Function |
| Protein Families | Transcription Factors |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "TORC1" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH306974 | CRTC1 MS Standard C13 and N15-labeled recombinant protein (NP_056136) | 10 ug |
$3,360.00
|
|
| LC414618 | Lyophilized CRTC1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC420588 | Lyophilized CRTC1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY414618 | Transient overexpression lysate of CREB regulated transcription coactivator 1 (CRTC1), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY420588 | Transient overexpression lysate of CREB regulated transcription coactivator 1 (CRTC1), transcript variant 3 (as WB positive control) | 100 ug |
$665.00
|
|
| TP306974 | Recombinant protein of human CREB regulated transcription coactivator 1 (CRTC1), transcript variant 1, 20 µg | 20 ug |
$737.00
|
|
| TP324693 | Recombinant protein of human CREB regulated transcription coactivator 1 (CRTC1), transcript variant 3, 20 µg | 20 ug |
$737.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
