RCCD1 (NM_001017919) Human Mass Spec Standard

SKU
PH322746
RCCD1 MS Standard C13 and N15-labeled recombinant protein (NP_001017919)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC222746
Predicted MW 39.9 kDa
Protein Sequence
Protein Sequence
>RC222746 representing NM_001017919
Red=Cloning site Green=Tags(s)

MAEERPGAWFGFGFCGFGQELGSGRGRQVHSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAA
GRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEAEGEDDPAGEAQAGRLPLLPCA
RAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQGL
VMAEVAAGGWHSVCVSETGDIYIWGWNESGQLALPTRNLAEDGETVAREATELNEDGSQVKRTGGAEDGA
PAPFIAVQPFPALLDLPMGSDAVKASCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLDRPRRVEYFV
DKQLQVKAVTCGPWNTYVYAVEKGKS

SGPTRTRRLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001017919
RefSeq Size 2690
RefSeq ORF 1128
Locus ID 91433
UniProt ID A6NED2
Cytogenetics 15q26.1
Summary Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8 (PubMed:24981860). Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation (PubMed:24981860). Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8 (PubMed:28455245).UniProtKB/Swiss-Prot Function
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Other "RCCD1" proteins (3)
SKU Description Size Price
LC422749 Lyophilized RCCD1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY422749 Transient overexpression lysate of RCC1 domain containing 1 (RCCD1), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP322746 Recombinant protein of human RCC1 domain containing 1 (RCCD1), transcript variant 2, 20 µg 20 ug
$867.00

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