D4S234E (NSG1) (NM_014392) Human Mass Spec Standard

SKU
PH322554
D4S234E MS Standard C13 and N15-labeled recombinant protein (NP_055207)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC222554
Predicted MW 20.7 kDa
Protein Sequence
Protein Sequence
>RC222554 representing NM_014392
Red=Cloning site Green=Tags(s)

MVKLGNNFAEKGTKQPLLEDGFDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYEPDRKKGKARPPQIAEFT
VSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDRACPDGFVLKNTQCIPEGLESYYAEQDSSAR
EKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLSEQETEAAEKSA

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_055207
RefSeq Size 1517
RefSeq ORF 555
Synonyms D4S234; D4S234E; NEEP21; P21
Locus ID 27065
UniProt ID P42857
Cytogenetics 4p16.3
Summary Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway. Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (By similarity). Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatodendritic early endosome or the recycling endosome (By similarity). In an other hand, induces apoptosis via the activation of CASP3 in response to DNA damage (PubMed:20599942, PubMed:20878061).UniProtKB/Swiss-Prot Function
Protein Families Druggable Genome, Transmembrane
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Other "D4S234E" proteins (5)
SKU Description Size Price
LC415315 Lyophilized NSG1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC421674 Lyophilized NSG1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY415315 Transient overexpression lysate of DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY421674 Transient overexpression lysate of DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP322554 Recombinant protein of human DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), transcript variant 1, 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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