PACRG (NM_001080378) Human Mass Spec Standard

CAT#: PH322240

PACRG MS Standard C13 and N15-labeled recombinant protein (NP_001073847)

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USD 1,995.00


Availability*
3 Weeks

Size
    • 10 ug

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Specifications

Product Data
Description PACRG MS Standard C13 and N15-labeled recombinant protein (NP_001073847)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC222240
Predicted MW 29.1 kDa
Protein Sequence
Tag C-MYC/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001073847
RefSeq Size 1585
RefSeq ORF 771
Synonyms GLUP; HAK005771; PARK2CRG
Locus ID 135138
Cytogenetics 6q26
Summary This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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