Hairless (HR) (NM_018411) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC221977 |
| Predicted MW | 121.7 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_060881 |
| RefSeq Size | 4816 |
| RefSeq ORF | 3402 |
| Synonyms | ALUNC; AU; HSA277165; HYPT4; MUHH; MUHH1 |
| Locus ID | 55806 |
| UniProt ID | O43593 |
| Cytogenetics | 8p21.3 |
| Summary | This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Oct 2014 |
| Protein Families | Druggable Genome, Transcription Factors |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Hairless" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH309010 | HR MS Standard C13 and N15-labeled recombinant protein (NP_005135) | 10 ug |
$3,360.00
|
|
| LC413066 | Lyophilized HR HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC417487 | Lyophilized HR HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY413066 | Transient overexpression lysate of hairless homolog (mouse) (HR), transcript variant 2 (as WB positive control) | 100 ug |
$665.00
|
|
| LY417487 | Transient overexpression lysate of hairless homolog (mouse) (HR), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP309010 | Recombinant protein of human hairless homolog (mouse) (HR), transcript variant 1, 20 µg | 20 ug |
$737.00
|
|
| TP321977 | Recombinant protein of human hairless homolog (mouse) (HR), transcript variant 2, 20 µg | 20 ug |
$737.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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