SKA1 (NM_001039535) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC221913 |
| Predicted MW | 29.5 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001034624 |
| RefSeq Size | 2938 |
| RefSeq ORF | 765 |
| Synonyms | C18orf24 |
| Locus ID | 220134 |
| UniProt ID | Q96BD8 |
| Cytogenetics | 18q21.1 |
| Summary | Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:17093495, PubMed:19289083, PubMed:23085020). Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint (PubMed:17093495). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020). In the complex, it mediates the interaction with microtubules (PubMed:19289083, PubMed:23085020).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "SKA1" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH302370 | SKA1 MS Standard C13 and N15-labeled recombinant protein (NP_659497) | 10 ug |
$3,360.00
|
|
| LC408057 | Lyophilized SKA1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC422066 | Lyophilized SKA1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY408057 | Transient overexpression lysate of spindle and kinetochore associated complex subunit 1 (SKA1), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY422066 | Transient overexpression lysate of spindle and kinetochore associated complex subunit 1 (SKA1), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP302370 | Recombinant protein of human chromosome 18 open reading frame 24 (C18orf24), transcript variant 2, 20 µg | 20 ug |
$867.00
|
|
| TP321913 | Recombinant protein of human chromosome 18 open reading frame 24 (C18orf24), transcript variant 1, 20 µg | 20 ug |
$867.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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