RCC1 (NM_001269) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC221798 |
| Predicted MW | 45 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001260 |
| RefSeq Size | 2540 |
| RefSeq ORF | 1263 |
| Synonyms | CHC1; RCC1-I; SNHG3-RCC1 |
| Locus ID | 1104 |
| UniProt ID | P18754 |
| Cytogenetics | 1p35.3 |
| Summary | Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis (PubMed:1944575, PubMed:17435751, PubMed:20668449, PubMed:22215983, PubMed:11336674). Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis (PubMed:12194828, PubMed:17435751, PubMed:22215983). Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import (PubMed:22215983). Involved in the regulation of onset of chromosome condensation in the S phase (PubMed:3678831). Binds both to the nucleosomes and double-stranded DNA (PubMed:17435751, PubMed:18762580).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "RCC1" proteins (9)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH303556 | SNHG3 MS Standard C13 and N15-labeled recombinant protein (NP_001041664) | 10 ug |
$3,360.00
|
|
| LC420036 | Lyophilized RCC1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC420775 | Lyophilized RCC1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC420778 | Lyophilized RCC1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY420036 | Transient overexpression lysate of regulator of chromosome condensation 1 (RCC1), transcript variant 3 (as WB positive control) | 100 ug |
$665.00
|
|
| LY420775 | Transient overexpression lysate of regulator of chromosome condensation 1 (RCC1), transcript variant 2 (as WB positive control) | 100 ug |
$665.00
|
|
| LY420778 | Transient overexpression lysate of SNHG3-RCC1 readthrough transcript (SNHG3-RCC1), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP303556 | Recombinant protein of human SNHG3-RCC1 readthrough transcript (SNHG3-RCC1), transcript variant 3, 20 µg | 20 ug |
$737.00
|
|
| TP321798 | Recombinant protein of human regulator of chromosome condensation 1 (RCC1), transcript variant 3, 20 µg | 20 ug |
$737.00
|
|
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.