SNRPN (NM_022805) Human Mass Spec Standard

SKU
PH320680
SNRPN MS Standard C13 and N15-labeled recombinant protein (NP_073716)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220680
Predicted MW 24.6 kDa
Protein Sequence
Protein Sequence
>RC220680 protein sequence
Red=Cloning site Green=Tags(s)

MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKRVLGLV
LLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQ
VMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARG
TPIGMPPPGMRPPPPGIRGPPPPGMRPPRP

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_073716
RefSeq Size 1605
RefSeq ORF 720
Synonyms HCERN3; PWCR; PWS; RT-LI; SM-D; sm-N; SMN; SNRNP-N; SNURF-SNRPN
Locus ID 6638
UniProt ID P63162
Cytogenetics 15q11.2
Summary This gene is located within the Prader-Willi Syndrome critical region on chromosome 15 and is imprinted and expressed from the paternal allele. It encodes a component of the small nuclear ribonucleoprotein complex, which functions in pre-mRNA processing and may contribute to tissue-specific alternative splicing. Alternative promoter use and alternative splicing result in a multitude of transcript variants encoding the same protein. Transcript variants that initiate at the CpG island-associated imprinting center may be bicistronic and also encode the SNRPN upstream reading frame protein (SNURF) from an upstream open reading frame. In addition, long spliced transcripts for small nucleolar RNA host gene 14 (SNHG14) may originate from the promoters at this locus and share exons with this gene. Alterations in this region are associated with parental imprint switch failure, which may cause Angelman syndrome or Prader-Willi syndrome. provided by RefSeq, Mar 2017
Protein Families Stem cell - Pluripotency
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Documents
Resources
Other "SNRPN" proteins (11)
SKU Description Size Price
LC401079 Lyophilized SNRPN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC411550 Lyophilized SNRPN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC411551 Lyophilized SNRPN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC411552 Lyophilized SNRPN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC411553 Lyophilized SNRPN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401079 Transient overexpression lysate of small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY411550 Transient overexpression lysate of small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY411551 Transient overexpression lysate of small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 3 (as WB positive control) 100 ug
$436.00
LY411552 Transient overexpression lysate of small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 4 (as WB positive control) 100 ug
$436.00
LY411553 Transient overexpression lysate of small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 5 (as WB positive control) 100 ug
$436.00
TP320680 Recombinant protein of human small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 2, 20 µg 20 ug
$867.00

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