CTPS2 (NM_175859) Human Mass Spec Standard

SKU
PH320566
CTPS2 MS Standard C13 and N15-labeled recombinant protein (NP_787055)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220566
Predicted MW 65.7 kDa
Protein Sequence
Protein Sequence
>RC220566 protein sequence
Red=Cloning site Green=Tags(s)

MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLD
LGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQAKVPVDGNKEEP
QICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQLSATGEQKTKPTQNSVRALRGLGLS
PDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSTYRVPVLLEEQSIVKYFKERLHLPIGDSASN
LLFKWRNMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEKITETED
PVKFHEAWQKLCKADGILVPGGFGIRGTLGKLQAISWARTKKIPFLGVCLGMQLAVIEFARNCLNLKDAD
STEFRPNAPVPLVIDMPEHNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRHRFEVNPNLIK
QFEQNDLSFVGQDVDGDRMEIIELANHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAYLQQGCK
LSSSDRYSDASDDSFSEPRIAELEIS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_787055
RefSeq Size 3973
RefSeq ORF 1758
Synonyms GATD5B
Locus ID 56474
UniProt ID Q9NRF8
Cytogenetics Xp22.2
Summary The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2013
Protein Pathways Metabolic pathways, Pyrimidine metabolism
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LC428462 Lyophilized CTPS2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LY406236 Transient overexpression lysate of CTP synthase II (CTPS2), transcript variant 2 (as WB positive control) 100 ug
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LY412688 Transient overexpression lysate of CTP synthase II (CTPS2), transcript variant 1 (as WB positive control) 100 ug
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LY428462 Transient overexpression lysate of CTP synthase II (CTPS2), transcript variant 3 (as WB positive control) 100 ug
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TP305993 Recombinant protein of human CTP synthase II (CTPS2), transcript variant 1, 20 µg 20 ug
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TP320566 Recombinant protein of human CTP synthase II (CTPS2), transcript variant 2, 20 µg 20 ug
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TP326565 Recombinant protein of human CTP synthase II (CTPS2), transcript variant 3, 20 µg 20 ug
$737.00

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