FGFR4 (NM_022963) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC219813 |
| Predicted MW | 80.9 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_075252 |
| RefSeq Size | 2807 |
| RefSeq ORF | 2286 |
| Synonyms | CD334; JTK2; TKF |
| Locus ID | 2264 |
| UniProt ID | P22455 |
| Cytogenetics | 5q35.2 |
| Summary | The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. provided by RefSeq, Aug 2017 |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Endocytosis, MAPK signaling pathway, Regulation of actin cytoskeleton |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "FGFR4" proteins (12)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC400735 | Lyophilized FGFR4 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC403876 | Lyophilized FGFR4 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC411457 | Lyophilized FGFR4 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC429711 | Lyophilized FGFR4 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC431021 | Lyophilized FGFR4 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400735 | Transient overexpression lysate of fibroblast growth factor receptor 4 (FGFR4), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY403876 | Transient overexpression lysate of fibroblast growth factor receptor 4 (FGFR4), transcript variant 3 (as WB positive control) | 100 ug |
$665.00
|
|
| LY411457 | Transient overexpression lysate of fibroblast growth factor receptor 4 (FGFR4), transcript variant 2 (as WB positive control) | 100 ug |
$665.00
|
|
| LY429711 | Transient overexpression lysate of fibroblast growth factor receptor 4 (FGFR4), transcript variant 2 (as WB positive control) | 100 ug |
$665.00
|
|
| LY431021 | Transient overexpression lysate of fibroblast growth factor receptor 4 (FGFR4), transcript variant 3 (as WB positive control) | 100 ug |
$665.00
|
|
| TP319813 | Recombinant protein of human fibroblast growth factor receptor 4 (FGFR4), transcript variant 2, 20 µg | 20 ug |
$737.00
|
|
| TP700125 | Purified recombinant protein of human fibroblast growth factor receptor 4 (FGFR4), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 µg | 20 ug |
$900.00
|
|
Citations
Nuclear localization of folate receptor alpha: a new role as a transcription factor
Boshnjaku, Shim, Tsurubuchi et al
Sci Rep (2012) 2, 980 DOI: 10.1038/srep00980
Boshnjaku, Shim, Tsurubuchi et al
Sci Rep (2012) 2, 980 DOI: 10.1038/srep00980
Cited by 118
AI Summary: OriGene’s MegaTran 1.0 transfection reagent (Cat#: TT200003) was used for co-transfecting cells with human FRα cDNA and promoter constructs, enabling the study of FRα’s novel role as a transcription factor in this paper.
Snippet: For co-transfections: human FRα cDNA and mouse Hes1-Luc promoter or human FRα cDNA and human FGFR4-Luc promoter were transfected into the cells using MegaTran 1.0 from OriGene;Cat#: TT200003. After 24 h, FA was added to the treatment wells.
Showing 1-1 of 1 papers.
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