HCST (NM_001007469) Human Mass Spec Standard

SKU
PH319253
HCST MS Standard C13 and N15-labeled recombinant protein (NP_001007470)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC219253
Predicted MW 9.5 kDa
Protein Sequence
Protein Sequence
>RC219253 protein sequence
Red=Cloning site Green=Tags(s)

MIHLGHILFLLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVASLLIVGAVFL
CARPRRSPAQEDGKVYINMPGRG

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001007470
RefSeq Size 521
RefSeq ORF 279
Synonyms DAP10; KAP10; PIK3AP
Locus ID 10870
UniProt ID Q9UBK5
Cytogenetics 19q13.12
Summary This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. provided by RefSeq, Jul 2008
Protein Families Druggable Genome, Transmembrane
Protein Pathways Natural killer cell mediated cytotoxicity
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Other "HCST" proteins (5)
SKU Description Size Price
LC402299 Lyophilized HCST HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC423490 Lyophilized HCST HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY402299 Transient overexpression lysate of hematopoietic cell signal transducer (HCST), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY423490 Transient overexpression lysate of hematopoietic cell signal transducer (HCST), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP319253 Recombinant protein of human hematopoietic cell signal transducer (HCST), transcript variant 2, 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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