SNX27 (NM_030918) Human Mass Spec Standard

SKU
PH318477
SNX27 MS Standard C13 and N15-labeled recombinant protein (NP_112180)
  $3,360.00
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC218477
Predicted MW 59.6 kDa
Protein Sequence
Protein Sequence
>RC218477 representing NM_030918
Red=Cloning site Green=Tags(s)

MADEDGEGIHPSAPHRNGGGGGGGGSGLHCAGNGGGGGGGPRVVRIVKSESGYGFNVRGQVSEGGQLRSI
NGELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNHVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEA
DNLDPSDDSLGQSFYDYTEKQAVPISVPRYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKRE
FANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDENYNGVSDVELRVA
LPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPHKLYIQNYTSAV
PGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKSYQLQKLYEQRKMVMYLNMLRT
CEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRWDTDEEGMAFCFEY
ARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKEEY

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_112180
RefSeq Size 7085
RefSeq ORF 1584
Synonyms MRT1; MY014
Locus ID 81609
UniProt ID Q96L92
Cytogenetics 1q21.3
Summary This gene encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein. provided by RefSeq, Jul 2008
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Documents
Resources
Other "SNX27" proteins (3)
SKU Description Size Price
LC403094 Lyophilized SNX27 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY403094 Transient overexpression lysate of sorting nexin family member 27 (SNX27) (as WB positive control) 100 ug
$665.00
TP318477 Recombinant protein of human sorting nexin family member 27 (SNX27), 20 µg 20 ug
$737.00

file-alt Citations

A role for sorting nexin 27 in AMPA receptor trafficking
Loo, Tang, Al-Haddawi et al
Nat Commun (2014) 5, 3176 DOI: 10.1038/ncomms4176
Cited by 114
AI Summary: OriGene’s human SNX27 cDNA was used to generate GFP-SNX27 and mCherry-SNX27 constructs, enabling the study of SNX27’s localization and role in AMPA receptor trafficking in this paper.
Snippet: GFP-SNX27 and mCherry SNX27 were generated by subcloning human SNX27 (Origene) into pEGFP-N1 or pmCherry-N1 (Clontech) using Bgl11 and BamH1
Showing 1-1 of 1 papers.
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