C17orf71 (SMG8) (NM_018149) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC216692 |
| Predicted MW | 109.5 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_060619 |
| RefSeq Size | 3283 |
| RefSeq ORF | 2973 |
| Synonyms | C17orf71 |
| Locus ID | 55181 |
| UniProt ID | Q8ND04 |
| Cytogenetics | 17q22 |
| Summary | Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "C17orf71" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC413279 | Lyophilized SMG8 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY413279 | Transient overexpression lysate of chromosome 17 open reading frame 71 (C17orf71) (as WB positive control) | 100 ug |
$665.00
|
|
| TP316692 | Recombinant protein of human chromosome 17 open reading frame 71 (C17orf71), 20 µg | 20 ug |
$867.00
|
|
Citations
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