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SPC24 (NM_182513) Human Mass Spec Standard

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SKU
PH311241
SPC24 MS Standard C13 and N15-labeled recombinant protein (NP_872319)
Size:
10 ug
  $3,360.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA381921 SPC24 Rabbit polyclonal Antibody
100 ul
$410.00
LY405531 Transient overexpression lysate of SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) (SPC24) (as WB positive control) 100 ug
$436.00

Other products for "SPC24 or NM_182513"

Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC211241
Predicted MW 22.4 kDa
Protein Sequence
Protein Sequence
>RC211241 protein sequence
Red=Cloning site Green=Tags(s)

MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAK
EQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTIPSAVYVA
QLYHQVSKIEWDYECEPGMVKGIHHGPSVAQPIHLDSTQLSRKFISDYLWSLVDTEW

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_872319
RefSeq Size 654
RefSeq ORF 591
Synonyms SPBC24
Locus ID 147841
UniProt ID Q8NBT2
Cytogenetics 19p13.2
Summary Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:14738735). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:14738735). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020).UniProtKB/Swiss-Prot Function
Protein Families Druggable Genome
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Other "SPC24" proteins (3)
SKU Description Size Price
LC405531 Lyophilized SPC24 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY405531 Transient overexpression lysate of SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) (SPC24) (as WB positive control) 100 ug
$436.00
TP311241 Recombinant protein of human SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) (SPC24), 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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