COMP (NM_000095) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC211080 |
| Predicted MW | 82.9 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000086 |
| RefSeq Size | 2471 |
| RefSeq ORF | 2271 |
| Synonyms | CTS2; EDM1; EPD1; MED; PSACH; THBS5; TSP5 |
| Locus ID | 1311 |
| UniProt ID | P49747 |
| Cytogenetics | 19p13.11 |
| Summary | The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). provided by RefSeq, Jul 2016 |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | ECM-receptor interaction, Focal adhesion, TGF-beta signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "COMP" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC424929 | Lyophilized COMP HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY424929 | Transient overexpression lysate of cartilage oligomeric matrix protein (COMP) (as WB positive control) | 100 ug |
$436.00
|
|
| TP311080 | Recombinant protein of human cartilage oligomeric matrix protein (COMP), 20 µg | 20 ug |
$737.00
|
|
Citations
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