MC2 receptor (MC2R) (NM_000529) Human Mass Spec Standard

SKU
PH310483
MC2R MS Standard C13 and N15-labeled recombinant protein (NP_000520)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC210483
Predicted MW 33.9 kDa
Protein Sequence
Protein Sequence
>RC210483 protein sequence
Red=Cloning site Green=Tags(s)

MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVFKNKNLQAPMYFFICSLAISD
MLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHS
IVTMRRTVVVLTVIWTFCTGTGITMVIFSHHVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTL
PRANMKGAITLTILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRS
PELRDAFKKMIFCSRYW

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_000520
RefSeq Size 3652
RefSeq ORF 891
Synonyms ACTHR
Locus ID 4158
UniProt ID Q01718
Cytogenetics 18p11.21
Summary MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene. provided by RefSeq, May 2014
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Neuroactive ligand-receptor interaction
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Other "MC2 receptor" proteins (3)
SKU Description Size Price
LC400177 Lyophilized MC2R HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400177 Transient overexpression lysate of melanocortin 2 receptor (adrenocorticotropic hormone) (MC2R) (as WB positive control) 100 ug
$436.00
TP310483 Recombinant protein of human melanocortin 2 receptor (adrenocorticotropic hormone) (MC2R), 20 µg 20 ug
$737.00

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