Influenza Virus NS1A Binding Protein (IVNS1ABP) (NM_006469) Human Mass Spec Standard

SKU
PH309701
IVNS1ABP MS Standard C13 and N15-labeled recombinant protein (NP_006460)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209701
Predicted MW 71.7 kDa
Protein Sequence
Protein Sequence
>RC209701 protein sequence
Red=Cloning site Green=Tags(s)

MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDPHGI
SHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNF
ASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEVMLEDNVCLPSNGKLYTKVINWVQRSIWENG
DSLEELMGEVQTLYYSADHKLLDGNLLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISSSSTGCLSSPNA
TVQSPKHEWKIVASEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKP
MSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQLYVV
GGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVTK
LWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIAPMNVARRGAGVAVLNGK
LFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGIATVGNTIYAVGGFDGNEFLNTVEVYNLES
NEWSPYTKIFQF

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_006460
RefSeq Size 4113
RefSeq ORF 1926
Synonyms ARA3; FLARA3; HSPC068; IMD70; KLHL39; ND1; NS-1; NS1-BP; NS1BP
Locus ID 10625
UniProt ID Q9Y6Y0
Cytogenetics 1q25.3
Summary Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats (By similarity). Protects cells from cell death induced by actin destabilization (By similarity). Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription (PubMed:16582008). In addition, functions as a negative regulator of BCR(KLHL20) E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors (PubMed:25619834). Inhibits pre-mRNA splicing (in vitro) (PubMed:9696811).UniProtKB/Swiss-Prot Function
Protein Families Transcription Factors
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Documents
Resources
Other "Influenza Virus NS1A Binding Protein" proteins (3)
SKU Description Size Price
LC416621 Lyophilized IVNS1ABP HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY416621 Transient overexpression lysate of influenza virus NS1A binding protein (IVNS1ABP) (as WB positive control) 100 ug
$436.00
TP309701 Recombinant protein of human influenza virus NS1A binding protein (IVNS1ABP), 20 µg 20 ug
$737.00

file-alt Citations

Cellular RNA binding proteins NS1-BP and hnRNP K regulate influenza A virus RNA splicing
Tsai, Chiou, Kuss et al
PLoS Pathog. (2013) 9 (6), e1003460 DOI: 10.1371/journal.ppat.1003460
Cited by 95
AI Summary: OriGene’s full-length cDNA clone of human NS1-BP (NM_006469.4) was used in this study to investigate the role of NS1-BP in regulating influenza A virus RNA splicing.
Snippet: analysis. Each protein band in (A) and (B) was quantified by ImageJ and normalized to α-tubulin levels. ... trypsin. Plasmids. Full-length cDNA clone of human NS1-BP (NM_006469.4) was purchased from OriGene Technologies, Inc.
FigureFigureFigure
Showing 1-1 of 1 papers.
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