ZCCHC8 (NM_017612) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC209528 |
| Predicted MW | 78.6 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_060082 |
| RefSeq Size | 4260 |
| RefSeq ORF | 2121 |
| Synonyms | PFBMFT5 |
| Locus ID | 55596 |
| UniProt ID | Q6NZY4 |
| Cytogenetics | 12q24.31 |
| Summary | This gene encodes a scaffold protein which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal proline-rich domain. provided by RefSeq, Apr 2017 |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "ZCCHC8" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC413673 | Lyophilized ZCCHC8 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY413673 | Transient overexpression lysate of zinc finger, CCHC domain containing 8 (ZCCHC8) (as WB positive control) | 100 ug |
$436.00
|
|
| TP309528 | Recombinant protein of human zinc finger, CCHC domain containing 8 (ZCCHC8), 20 µg | 20 ug |
$737.00
|
|
Citations
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