NSMCE4A (NM_017615) Human Mass Spec Standard

SKU
PH309357
NSMCE4A MS Standard C13 and N15-labeled recombinant protein (NP_060085)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209357
Predicted MW 44.2 kDa
Protein Sequence
Protein Sequence
>RC209357 protein sequence
Red=Cloning site Green=Tags(s)

MSGDSSGRGPEGRGRGRDPHRDRTRSRSRSRSPLSPRSRRGSARERREAPERPSLEDTEPSDSGDEMMDP
ASLEAEADQGLCRQIRHQYRALINSVQQNREDILNAGDKLTEVLEEANTLFNEVSRAREAVLDAHFLVLA
SDLGKEKAKQLRSDLSSFDMLRYVETLLTHMGVNPLEAEELIRDEDSPDFEFIVYDSWKITGRTAENTFN
KTHTFHFLLGSIYGECPVPKPRVDRPRKVPVIQEERAMPAQLRRMEESHQEATEKEVERILGLLQTYFRE
DPDTPMSFFDFVVDPHSFPRTVENIFHVSFIIRDGFARIRLDQDRLPVIEPVSINEENEGFEHNTQVRNQ
GIIALSYRDWEEIVKTFEISEPVITPSQRQQKPSA

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_060085
RefSeq Size 1420
RefSeq ORF 1155
Synonyms C10orf86; NS4EA; NSE4A
Locus ID 54780
UniProt ID Q9NXX6
Cytogenetics 10q26.13
Summary Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Is involved in positive regulation of response to DNA damage stimulus.UniProtKB/Swiss-Prot Function
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Other "NSMCE4A" proteins (3)
SKU Description Size Price
LC413676 Lyophilized NSMCE4A HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY413676 Transient overexpression lysate of non-SMC element 4 homolog A (S. cerevisiae) (NSMCE4A), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP309357 Recombinant protein of human non-SMC element 4 homolog A (S. cerevisiae) (NSMCE4A), 20 µg 20 ug
$867.00

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