Desmocollin 2 (DSC2) (NM_024422) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC209218 |
| Predicted MW | 97 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_077740 |
| RefSeq Size | 5140 |
| RefSeq ORF | 2703 |
| Synonyms | ARVD11; CDHF2; DG2; DGII/III; DSC3 |
| Locus ID | 1824 |
| UniProt ID | Q02487 |
| Cytogenetics | 18q12.1 |
| Summary | This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. provided by RefSeq, Feb 2015 |
| Protein Families | Transmembrane |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Desmocollin 2" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH322207 | DSC2 MS Standard C13 and N15-labeled recombinant protein (NP_004940) | 10 ug |
$3,360.00
|
|
| LC417636 | Lyophilized DSC2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY417636 | Transient overexpression lysate of desmocollin 2 (DSC2), transcript variant Dsc2b (as WB positive control) | 100 ug |
$665.00
|
|
| TP309218 | Purified recombinant protein of Homo sapiens desmocollin 2 (DSC2), transcript variant Dsc2a, 20 µg | 20 ug |
$737.00
|
|
| TP322207 | Purified recombinant protein of Homo sapiens desmocollin 2 (DSC2), transcript variant Dsc2b, 20 µg | 20 ug |
$737.00
|
|
Citations
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