GRAP (NM_006613) Human Mass Spec Standard

SKU
PH308908
GRAP MS Standard C13 and N15-labeled recombinant protein (NP_006604)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC208908
Predicted MW 25.3 kDa
Protein Sequence
Protein Sequence
>RC208908 protein sequence
Red=Cloning site Green=Tags(s)

MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPWYSGRISRQLA
EEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEEKFNSLNELVDFYRTTTI
AKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQDPSQLSFRRGDIIEVLERPDPHWWRGRSCGRVGFFPRS
YVQPVHL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_006604
RefSeq Size 2089
RefSeq ORF 651
Synonyms DFNB114
Locus ID 10750
UniProt ID Q13588
Cytogenetics 17p11.2
Summary This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. provided by RefSeq, Jul 2012
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Other "GRAP" proteins (3)
SKU Description Size Price
LC416529 Lyophilized GRAP HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY416529 Transient overexpression lysate of GRB2-related adaptor protein (GRAP) (as WB positive control) 100 ug
$436.00
TP308908 Recombinant protein of human GRB2-related adaptor protein (GRAP), 20 µg 20 ug
$737.00

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