GUCY1B1 (NM_000857) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC208205 |
| Predicted MW | 70.5 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000848 |
| RefSeq Size | 3261 |
| RefSeq ORF | 1857 |
| Synonyms | GC-S-beta-1; GC-SB3; GUC1B3; GUCB3; GUCSB3; GUCY1B3 |
| Locus ID | 2983 |
| UniProt ID | Q02153 |
| Cytogenetics | 4q32.1 |
| Summary | This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. provided by RefSeq, May 2014 |
| Protein Families | Druggable Genome |
| Protein Pathways | Gap junction, Long-term depression, Purine metabolism, Vascular smooth muscle contraction |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "GUCY1B1" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC400302 | Lyophilized GUCY1B3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400302 | Transient overexpression lysate of guanylate cyclase 1, soluble, beta 3 (GUCY1B3) (as WB positive control) | 100 ug |
$436.00
|
|
| TP308205 | Recombinant protein of human guanylate cyclase 1, soluble, beta 3 (GUCY1B3), 20 µg | 20 ug |
$867.00
|
|
Citations
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