CA7 (NM_001014435) Human Mass Spec Standard

SKU
PH307575
CA7 MS Standard C13 and N15-labeled recombinant protein (NP_001014435)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207575
Predicted MW 23.5 kDa
Protein Sequence
Protein Sequence
RC207575
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001014435
RefSeq Size 1710
RefSeq ORF 627
Synonyms CA-VII; CAVII
Locus ID 766
UniProt ID P43166
Cytogenetics 16q22.1
Summary Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the brain and contributes to bicarbonate driven GABAergic neuron excitation. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. provided by RefSeq, Aug 2018
Protein Families Druggable Genome
Protein Pathways Nitrogen metabolism
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file-alt Citations

Essential role of carbonic anhydrase XII in secretory glands fluid and HCO3-Secretion revealed by disease causing human mutation
Hong, Muhammad, Zheng et al
J. Physiol. (Lond.) (2015)
AI Summary: OriGene products contributed to this study by providing human wild-type CA7 and CA12 cDNA in the pCMV6-AC-Myc DDK vector, as well as the pCMV6-AC-mKate vector, which were used for gene expression and functional analyses in secretory gland research.
Snippet: Louis, MO). Human wild-type CA7 and CA12 cDNA in pCMV6-AC-Myc DDK vector was purchased from Origene Tech. (Rockville, MD). ... 7 NBCe1-B were excised from the original vectors and transferred to pCMV6-AC-mKate (Origene Tech.) and pEGFP-C1, respectively ... Cite SaveSaving
Showing 1-1 of 1 papers.
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