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HEXO (ERI1) (NM_153332) Human Mass Spec Standard

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SKU
PH306777
ERI1 MS Standard C13 and N15-labeled recombinant protein (NP_699163)
Size:
10 ug
  $3,360.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA504134 ERI1 mouse monoclonal antibody, clone OTI1B3 (formerly 1B3) 100 ul
$447.00
LY407051 Transient overexpression lysate of exoribonuclease 1 (ERI1) (as WB positive control) 100 ug
$436.00

Other products for "HEXO or NM_153332"

Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC206777
Predicted MW 40.1 kDa
Protein Sequence
Protein Sequence
>RC206777 protein sequence
Red=Cloning site Green=Tags(s)

MEDPQSKEPAGEAVALALLESPRPEGGEEPPRPSPEETQQCKFDGQETKGSKFITSSASDFSDPVYKEIA
ITNGCINRMSKEELRAKLSEFKLETRGVKDVLKKRLKNYYKKQKLMLKESNFADSYYDYICIIDFEATCE
EGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKV
IDWMKLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIM
LEKLGMDYDGRPHCGLDDSKNIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFRK

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_699163
RefSeq Size 4615
RefSeq ORF 1047
Synonyms 3'HEXO; HEXO; THEX1
Locus ID 90459
UniProt ID Q8IV48
Cytogenetics 8p23.1
Summary RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.UniProtKB/Swiss-Prot Function
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Other "HEXO" proteins (3)
SKU Description Size Price
LC407051 Lyophilized ERI1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY407051 Transient overexpression lysate of exoribonuclease 1 (ERI1) (as WB positive control) 100 ug
$436.00
TP306777 Recombinant protein of human exoribonuclease 1 (ERI1), 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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