SIGLEC5 (NM_003830) Human Mass Spec Standard

SKU
PH306610
SIGLEC5 MS Standard C13 and N15-labeled recombinant protein (NP_003821)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC206610
Predicted MW 60.7 kDa
Protein Sequence
Protein Sequence
>RC206610 protein sequence
Red=Cloning site Green=Tags(s)

MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYA
EVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVT
ALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTN
LTCQMKRQGAQVTTERTVQLNVSYAPQTITIFRNGIALEILQNTSYLPVLEGQALRLLCDAPSNPPAHLS
WFQGSPALNATPISNTGILELRRVRSAEEGGFTCRAQHPLGFLQIFLNLSVYSLPQLLGPSCSWEAEGLH
CRCSFRARPAPSLCWRLEEKPLEGNSSQGSFKVNSSSAGPWANSSLILHGGLSSDLKVSCKAWNIYGSQS
GSVLLLQGRSNLGTGVVPAALGGAGVMALLCICLCLIFFLIVKARRKQAAGRPEKMDDEDPIMGTITSGS
RKKPWPDSAGDQASPPGDAPPLEEQKELHYASLSFSEMKSREPKDQEAPSTTEYSEIKTSK

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_003821
RefSeq Size 2523
RefSeq ORF 1653
Synonyms CD33L2; CD170; OB-BP2; OBBP2; SIGLEC-5
Locus ID 8778
UniProt ID O15389
Cytogenetics 19q13.41
Summary This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. provided by RefSeq, Feb 2012
Protein Families Druggable Genome, Transmembrane
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Other "SIGLEC5" proteins (3)
SKU Description Size Price
LC418402 Lyophilized SIGLEC5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY418402 Transient overexpression lysate of sialic acid binding Ig-like lectin 5 (SIGLEC5) (as WB positive control) 100 ug
$436.00
TP306610 Recombinant protein of human sialic acid binding Ig-like lectin 5 (SIGLEC5), 20 µg 20 ug
$737.00

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