LASS3 (CERS3) (NM_178842) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC205511 |
| Predicted MW | 46.2 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_849164 |
| RefSeq Size | 3894 |
| RefSeq ORF | 1149 |
| Synonyms | ARCI9; LASS3 |
| Locus ID | 204219 |
| UniProt ID | Q8IU89 |
| Cytogenetics | 15q26.3 |
| Summary | This gene is a member of the ceramide synthase family of genes. The ceramide synthase enzymes regulate sphingolipid synthesis by catalyzing the formation of ceramides from sphingoid base and acyl-coA substrates. This family member is involved in the synthesis of ceramides with ultra-long-chain acyl moieties (ULC-Cers), important to the epidermis in its role in creating a protective barrier from the environment. The protein encoded by this gene has also been implicated in modification of the lipid structures required for spermatogenesis. Mutations in this gene have been associated with male fertility defects, and epidermal defects, including ichthyosis. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Aug 2015 |
| Protein Families | Transcription Factors, Transmembrane |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "LASS3" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC405858 | Lyophilized CERS3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY405858 | Transient overexpression lysate of LAG1 homolog, ceramide synthase 3 (LASS3) (as WB positive control) | 100 ug |
$436.00
|
|
| TP305511 | Recombinant protein of human LAG1 homolog, ceramide synthase 3 (LASS3), 20 µg | 20 ug |
$867.00
|
|
Citations
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