MICA (NM_000247) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC204447 |
| Predicted MW | 42.9 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000238 |
| RefSeq Size | 1410 |
| RefSeq ORF | 1149 |
| Synonyms | MIC-A; PERB11.1 |
| Locus ID | 100507436 |
| UniProt ID | Q29983 |
| Cytogenetics | 6p21.33 |
| Summary | This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. provided by RefSeq, Jan 2014 |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "MICA" proteins (8)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC400095 | Lyophilized MICA HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC432900 | Lyophilized MICA HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400095 | Transient overexpression lysate of MHC class I polypeptide-related sequence A (MICA) (as WB positive control) | 100 ug |
$436.00
|
|
| LY432900 | Transient overexpression lysate of MHC class I polypeptide-related sequence A (MICA), transcript variant 1 (allele MICA*00801) (as WB positive control) | 100 ug |
$436.00
|
|
| TP304447 | Recombinant protein of human MHC class I polypeptide-related sequence A (MICA), 20 µg | 20 ug |
$737.00
|
|
| TP329900 | Purified recombinant protein of Homo sapiens MHC class I polypeptide-related sequence A (MICA), transcript variant 1 (allele MICA*00801), 20 µg | 20 ug |
$737.00
|
|
| TP720672 | Purified recombinant protein of Human MHC class I polypeptide-related sequence A (MICA), transcript variant 1 (allele MICA*001) | 10 ug |
$220.00
|
|
| TP720954 | Purified recombinant protein of Human MHC class I polypeptide-related sequence A (MICA), transcript variant 1 (allele MICA*001) | 10 ug |
$260.00
|
|
Citations
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