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ROC2 (RNF7) (NM_014245) Human Mass Spec Standard

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SKU
PH303831
RNF7 MS Standard C13 and N15-labeled recombinant protein (NP_055060)
Size:
10 ug
  $3,360.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA364978 RNF7 rabbit polyclonal antibody
100 ul
$310.00
LY402297 Transient overexpression lysate of ring finger protein 7 (RNF7), transcript variant 1 (as WB positive control) 100 ug
$436.00

Other products for "ROC2 or NM_014245"

Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203831
Predicted MW 12.7 kDa
Protein Sequence
Protein Sequence
>RC203831 protein sequence
Red=Cloning site Green=Tags(s)

MADVEDGEETCALASHSGSSGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDACLRCQAENKQ
EDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIGK

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_055060
RefSeq Size 2010
RefSeq ORF 339
Synonyms CKBBP1; rbx2; ROC2; SAG
Locus ID 9616
UniProt ID Q9UBF6
Cytogenetics 3q23
Summary The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. provided by RefSeq, Jul 2008
Protein Families Druggable Genome
Protein Pathways Ubiquitin mediated proteolysis
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Other "ROC2" proteins (3)
SKU Description Size Price
LC402297 Lyophilized RNF7 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY402297 Transient overexpression lysate of ring finger protein 7 (RNF7), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP303831 Recombinant protein of human ring finger protein 7 (RNF7), transcript variant 1, 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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