ALIX (PDCD6IP) (NM_013374) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC203735 |
| Predicted MW | 96 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_037506 |
| RefSeq Size | 5972 |
| RefSeq ORF | 2604 |
| Synonyms | AIP1; ALIX; DRIP4; HP95 |
| Locus ID | 10015 |
| UniProt ID | Q8WUM4 |
| Cytogenetics | 3p22.3 |
| Summary | This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. provided by RefSeq, Jan 2012 |
| Protein Families | Druggable Genome |
| Protein Pathways | Endocytosis |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "ALIX" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC415634 | Lyophilized PDCD6IP HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY415634 | Transient overexpression lysate of programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP303735 | Recombinant protein of human programmed cell death 6 interacting protein (PDCD6IP), 20 µg | 20 ug |
$867.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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