DEM1 (EXO5) (NM_022774) Human Mass Spec Standard

SKU
PH303370
DEM1 MS Standard C13 and N15-labeled recombinant protein (NP_073611)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203370
Predicted MW 41.9 kDa
Protein Sequence
Protein Sequence
>RC203370 protein sequence
Red=Cloning site Green=Tags(s)

MAETREEETVSAEASGFSDLSDSEFLEFLDLEDAQESKALVNMPGPSSESLGKDDKPISLQNWKRGLDIL
SPMERFHLKYLYVTDLATQNWCELQTAYGKELPGFLAPEKAAVLDTGASIHLARELELHDLVTVPVTTKE
DAWAIKFLNILLLIPTLQSEGHIREFPVFGEVEGVLLVGVIDELHYTAKGELELAELKTRRRPMLPLEAQ
KKKDCFQVSLYKYIFDAMVQGKVTPASLIHHTKLCLEKPLGPSVLRHAQQGGFSVKSLGDLMELVFLSLT
LSDLPVIDILKIEYIHQETATVLGTEIVAFKEKEVRAKVQHYMAYWMGHREPQGVDVEEAWKCRTCTYAD
ICEWRKGSGVLSSTLAPQVKKAK

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_073611
RefSeq Size 2217
RefSeq ORF 1119
Synonyms C1orf176; DEM1; Exo V; hExo5
Locus ID 64789
UniProt ID Q9H790
Cytogenetics 1p34.2
Summary The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5'-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage. provided by RefSeq, Nov 2016
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Other "DEM1" proteins (3)
SKU Description Size Price
LC411564 Lyophilized EXO5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY411564 Transient overexpression lysate of defects in morphology 1 homolog (S. cerevisiae) (DEM1) (as WB positive control) 100 ug
$436.00
TP303370 Recombinant protein of human defects in morphology 1 homolog (S. cerevisiae) (DEM1), 20 µg 20 ug
$737.00

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