WFS1 (NM_006005) Human Mass Spec Standard

SKU
PH302901
WFS1 MS Standard C13 and N15-labeled recombinant protein (NP_005996)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202901
Predicted MW 100.3 kDa
Protein Sequence
Protein Sequence
>RC202901 protein sequence
Red=Cloning site Green=Tags(s)

MDSNTAPLGPSCPQPPPAPQPQARSRLNATASLEQERSERPRAPGPQAGPGPGVRDAAAPAEPQAQHTRS
RERADGTGPTKGDMEIPFEEVLERAKAGDPKAQTEVGKHYLQLAGDTDEELNSCTAVDWLVLAAKQGRRE
AVKLLRRCLADRRGITSENEREVRQLSSETDLERAVRKAALVMYWKLNPKKKKQVAVAELLENVGQVNEH
DGGAQPGPVPKSLQKQRRMLERLVSSESKNYIALDDFVEITKKYAKGVIPSSLFLQDDEDDDELAGKSPE
DLPLRLKVVKYPLHAIMEIKEYLIDMASRAGMHWLSTIIPTHHINALIFFFIVSNLTIDFFAFFIPLVIF
YLSFISMVICTLKVFQDSKAWENFRTLTDLLLRFEPNLDVEQAEVNFGWNHLEPYAHFLLSVFFVIFSFP
IASKDCIPCSELAVITGFFTVTSYLSLSTHAEPYTRRALATEVTAGLLSLLPSMPLNWPYLKVLGQTFIT
VPVGHLVVLNVSVPCLLYVYLLYLFFRMAQLRNFKGTYCYLVPYLVCFMWCELSVVILLESTGLGLLRAS
IGYFLFLFALPILVAGLALVGVLQFARWFTSLELTKIAVTVAVCSVPLLLRWWTKASFSVVGMVKSLTRS
SMVKLILVWLTAIVLFCWFYVYRSEGMKVYNSTLTWQQYGALCGPRAWKETNMARTQILCSHLEGHRVTW
TGRFKYVRVTDIDNSAESAINMLPFFIGDWMRCLYGEAYPACSPGNTSTAEEELCRLKLLAKHPCHIKKF
DRYKFEITVGMPFSSGADGSRSREEDDVTKDIVLRASSEFKSVLLSLRQGSLIEFSTILEGRLGSKWPVF
ELKAISCLNCMAQLSPTRRHVKIEHDWRSTVHGAVKFAFDFFFFPFLSAA

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_005996
RefSeq Size 3640
RefSeq ORF 2670
Synonyms CTRCT41; WFRS; WFS; WFSL
Locus ID 7466
UniProt ID O76024
Cytogenetics 4p16.1
Summary This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Mar 2009
Protein Families Druggable Genome, Transmembrane
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Other "WFS1" proteins (7)
SKU Description Size Price
PH327925 WFS1 MS Standard C13 and N15-labeled recombinant protein (NP_001139325) 10 ug
$3,360.00
LC416929 Lyophilized WFS1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC429034 Lyophilized WFS1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY416929 Transient overexpression lysate of Wolfram syndrome 1 (wolframin) (WFS1), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY429034 Transient overexpression lysate of Wolfram syndrome 1 (wolframin) (WFS1), transcript variant 2 (as WB positive control) 100 ug
$665.00
TP302901 Purified recombinant protein of Homo sapiens Wolfram syndrome 1 (wolframin) (WFS1), transcript variant 1, 20 µg 20 ug
$737.00
TP327925 Purified recombinant protein of Homo sapiens Wolfram syndrome 1 (wolframin) (WFS1), transcript variant 2, 20 µg 20 ug
$737.00

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