Nck beta (NCK2) (NM_003581) Human Mass Spec Standard

SKU
PH302557
NCK2 MS Standard C13 and N15-labeled recombinant protein (NP_003572)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202557
Predicted MW 42.9 kDa
Protein Sequence
Protein Sequence
>RC202557 protein sequence
Red=Cloning site Green=Tags(s)

MTEEVIVIAKWDYTAQQDQELDIKKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKNSLKKGSLVKN
LKDTLGLGKTRRKTSARDASPTPSTDAEYPANGSGADRIYDLNIPAFVKFAYVAEREDELSLVKGSRVTV
MEKCSDGWWRGSYNGQIGWFPSNYVLEEVDEAAAESPSFLSLRKGASLSNGQGSRVLHVVQTLYPFSSVT
EEELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDGPALHPAHAPQISYTGPSSSGRF
AGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYCIGQRRFH
TMDELVEHYKKAPIFTSEHGEKLYLVRALQ

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_003572
RefSeq Size 2517
RefSeq ORF 1140
Synonyms GRB4; NCKbeta
Locus ID 8440
UniProt ID O43639
Cytogenetics 2q12.2
Summary This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. provided by RefSeq, Jul 2008
Protein Families Druggable Genome
Protein Pathways Axon guidance, ErbB signaling pathway, Pathogenic Escherichia coli infection, T cell receptor signaling pathway
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Other "Nck beta" proteins (7)
SKU Description Size Price
PH300449 NCK2 MS Standard C13 and N15-labeled recombinant protein (NP_001004720) 10 ug
$3,360.00
LC401190 Lyophilized NCK2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC423904 Lyophilized NCK2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401190 Transient overexpression lysate of NCK adaptor protein 2 (NCK2), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY423904 Transient overexpression lysate of NCK adaptor protein 2 (NCK2), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP300449 Recombinant protein of human NCK adaptor protein 2 (NCK2), transcript variant 2, 20 µg 20 ug
$867.00
TP302557 Recombinant protein of human NCK adaptor protein 2 (NCK2), transcript variant 1, 20 µg 20 ug
$867.00

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